Effect of Obstructive Sleep Apnea on Amyloid Burden Lead Investigator: Ram Sharma Institution : New York University E-Mail : ram.sharma@nyumc.org Proposal ID : 880 Proposal Description: Goals: To assess effect of obstructive sleep apnea on amyloid burden. Objectives: 1.To test the hypothesis that obstructive sleep apnea increases amyloid burden in cognitively normal elderly over a period of time. 2.Does obstructive sleep apnea decreases the clearance of amyloid beta from brain in cognitively normal elderly